It promises to be a good game with both sides likely to play free-flowing, attacking football throughout the contest.
United will be strong favourites with most bookmakers for this clash with the Championship side, with Mourinho unlikely to make any drastic changes to his starting eleven.
Bristol City have knocked out top-flight opposition on three occasions in the League Cup this season, downing Watford, Stoke and Crystal Palace – but Man United is probably going to be a stretch too far for the Robins.
Paul Pogba is likely to start the match, whilst Henrikh Mkhitaryan is also set to feature for the Red Devils.
Meanwhile David de Gea and Nemanja Matic are likely to be rested.
United fans…. Will you overcome the Robins? Let us know!